KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXT2
All Species:
17.27
Human Site:
Y566
Identified Species:
38
UniProt:
Q93063
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q93063
NP_000392.2
718
82255
Y566
F
P
D
R
L
V
G
Y
P
G
R
L
H
L
W
Chimpanzee
Pan troglodytes
XP_508383
781
88771
P616
P
P
E
D
S
L
W
P
K
I
R
V
P
L
K
Rhesus Macaque
Macaca mulatta
XP_001106468
755
86216
P590
P
P
E
D
S
L
W
P
K
I
R
V
P
L
K
Dog
Lupus familis
XP_533196
718
82302
Y566
F
P
D
R
L
V
G
Y
P
G
R
L
H
L
W
Cat
Felis silvestris
Mouse
Mus musculus
P70428
718
82087
Y566
F
P
D
R
L
V
G
Y
P
G
R
L
H
L
W
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510258
762
86239
G566
D
G
I
P
P
V
C
G
D
I
E
P
L
G
I
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080448
718
82063
Y566
F
P
D
R
L
V
G
Y
P
G
R
L
H
L
W
Zebra Danio
Brachydanio rerio
Q5IGR8
730
84599
Y576
F
P
E
R
I
V
G
Y
P
A
R
S
H
F
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9Y169
717
82708
F565
F
P
D
H
I
V
G
F
P
S
R
I
H
V
W
Honey Bee
Apis mellifera
XP_001121972
669
76885
W531
W
D
N
G
T
N
C
W
K
Y
E
S
E
W
T
Nematode Worm
Caenorhab. elegans
O01705
814
94178
P669
R
D
R
I
V
G
F
P
A
R
H
H
A
R
Y
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.8
85.6
97.4
N.A.
95.2
N.A.
N.A.
70.4
N.A.
85.7
35.3
N.A.
46.3
50
26
N.A.
Protein Similarity:
100
84.6
87.1
99.3
N.A.
97.3
N.A.
N.A.
78.6
N.A.
94.7
54.9
N.A.
66.7
68.2
45.3
N.A.
P-Site Identity:
100
20
20
100
N.A.
100
N.A.
N.A.
6.6
N.A.
100
66.6
N.A.
60
0
0
N.A.
P-Site Similarity:
100
40
40
100
N.A.
100
N.A.
N.A.
6.6
N.A.
100
80
N.A.
86.6
20
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
10
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
19
0
0
0
0
0
0
0
0
% C
% Asp:
10
19
46
19
0
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
0
0
28
0
0
0
0
0
0
0
19
0
10
0
0
% E
% Phe:
55
0
0
0
0
0
10
10
0
0
0
0
0
10
0
% F
% Gly:
0
10
0
10
0
10
55
10
0
37
0
0
0
10
0
% G
% His:
0
0
0
10
0
0
0
0
0
0
10
10
55
0
0
% H
% Ile:
0
0
10
10
19
0
0
0
0
28
0
10
0
0
10
% I
% Lys:
0
0
0
0
0
0
0
0
28
0
0
0
0
0
19
% K
% Leu:
0
0
0
0
37
19
0
0
0
0
0
37
10
55
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
19
73
0
10
10
0
0
28
55
0
0
10
19
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
0
10
46
0
0
0
0
0
10
73
0
0
10
0
% R
% Ser:
0
0
0
0
19
0
0
0
0
10
0
19
0
0
0
% S
% Thr:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
10
% T
% Val:
0
0
0
0
10
64
0
0
0
0
0
19
0
10
0
% V
% Trp:
10
0
0
0
0
0
19
10
0
0
0
0
0
10
55
% W
% Tyr:
0
0
0
0
0
0
0
46
0
10
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _